Safety of hormone replacement therapy after mastectomy
نویسندگان
چکیده
منابع مشابه
Safety of hormone replacement therapy after mastectomy.
Clinical question After mastectomy, chemotherapy and radiotherapy for high-grade ductal carcinoma with nodal involvement and lymphatic infiltration, a 48-year-old woman had premature menopause, with symptoms of loss of libido. Her general practitioner wanted to know how safe and effective hormone replacement therapy (HRT) would be for this patient. The revised question was: " Does HRT increase ...
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PURPOSE OF REVIEW The role of female hormones in estrogen-dependent cancers has been debated for years. This is particularly true of breast cancer. Retrospective, case, and cohort control studies usually have suggested no influence. The Women's Health Initiative study in 2002, a prospective double-blind study, noted an increased risk of breast cancer if estrogen plus progesterone was given. In ...
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In France, the National Collective Statement from the INSERM [1] recommends a prophylactic adnexectomy (PA) in women having an increased ovarian cancer risk due to mutations in BRCA1 or BRCA2 either at 40 years of age or at 35 years of age if the woman has decided she no longer wants children. PA can reduce the risks of ovarian cancer by more than 90% and breast cancer by more than 50%. However...
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متن کاملHormone replacement therapy.
HRT is indicated for the treatment of moderate ▪ to severe vasomotor and urogenital symptoms associated with menopause. HRT is not recommended for primary prevention of ▪ disease because of increased risk of other adverse events. The use of HRT increases the risk of stroke, venous ▪ thromboembolism (VTE) and gall bladder disease and combined oestrogen progestogen therapy is also associated with...
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ژورنال
عنوان ژورنال: Medical Journal of Australia
سال: 2002
ISSN: 0025-729X,1326-5377
DOI: 10.5694/j.1326-5377.2002.tb04600.x